diff --git a/build/autoconf/compiler-opts.m4 b/build/autoconf/compiler-opts.m4
index 68960acbc136..268c2d2f5a42 100644
--- a/build/autoconf/compiler-opts.m4
+++ b/build/autoconf/compiler-opts.m4
@@ -31,12 +31,6 @@ dnl ========================================================
 AC_DEFUN([MOZ_DEBUGGING_OPTS],
 [
 
-if test -z "$MOZ_DEBUG" -o -n "$MOZ_ASAN"; then
-    MOZ_NO_DEBUG_RTL=1
-fi
-
-AC_SUBST(MOZ_NO_DEBUG_RTL)
-
 if test -n "$MOZ_DEBUG"; then
     if test -n "$COMPILE_ENVIRONMENT"; then
         AC_MSG_CHECKING([for valid debug flags])
diff --git a/build/moz.configure/flags.configure b/build/moz.configure/flags.configure
index d07d31f71344..1bf155989f07 100644
--- a/build/moz.configure/flags.configure
+++ b/build/moz.configure/flags.configure
@@ -100,6 +100,20 @@ def pass_manager(enabled, compiler, host, target, pgo, enable_fuzzing, ubsan):
 
 set_config("MOZ_PASS_MANAGER_FLAGS", pass_manager.flags)
 
+# Debugging options
+##
+
+
+@depends(moz_debug, asan, target, "--enable-jemalloc")
+def moz_no_debug_rtl(moz_debug, asan, target, enable_jemalloc):
+    if not moz_debug or asan:
+        return True
+    if enable_jemalloc and target.kernel == "WINNT":
+        return True
+
+
+set_config("MOZ_NO_DEBUG_RTL", moz_no_debug_rtl)
+
 
 # Try to make builds more reproducible and allow sharing built artifacts across
 # source and object directories by using -ffile-prefix-map and friends.  To
diff --git a/js/src/old-configure.in b/js/src/old-configure.in
index a55b25273d31..e1861f3c4f22 100644
--- a/js/src/old-configure.in
+++ b/js/src/old-configure.in
@@ -669,13 +669,6 @@ else
   esac
 fi
 
-if test "$MOZ_MEMORY"; then
-  case "${target}" in
-  *-mingw*)
-    export MOZ_NO_DEBUG_RTL=1
-    ;;
-  esac
-fi
 AC_SUBST(MOZ_GLUE_IN_PROGRAM)
 
 dnl ========================================================
diff --git a/old-configure.in b/old-configure.in
index 5729a2f4b2a7..f3c08f327c82 100644
--- a/old-configure.in
+++ b/old-configure.in
@@ -766,17 +766,6 @@ Android|WINNT|Darwin)
   AC_DEFINE(MOZ_GLUE_IN_PROGRAM)
   ;;
 esac
-
-dnl ========================================================
-dnl = Jemalloc build setup
-dnl ========================================================
-if test -n "$MOZ_MEMORY"; then
-  case "${target}" in
-  *-mingw*)
-    export MOZ_NO_DEBUG_RTL=1
-    ;;
-  esac
-fi # MOZ_MEMORY
 AC_SUBST(MOZ_GLUE_IN_PROGRAM)
 
 dnl ========================================================