diff --git a/build/mach_initialize.py b/build/mach_initialize.py
index 4a93d0199f02..d05c2c170bfd 100644
--- a/build/mach_initialize.py
+++ b/build/mach_initialize.py
@@ -146,14 +146,12 @@ def initialize(topsrcdir, args=()):
         shutil.rmtree(deleted_dir, ignore_errors=True)
 
     # We need the "mach" module to access the logic to parse virtualenv
-    # requirements. Since that depends on "packaging" (and, transitively,
-    # "pyparsing"), we add those to the path too.
+    # requirements. Since that depends on "packaging", we add it to the path too.
     sys.path[0:0] = [
         os.path.join(topsrcdir, module)
         for module in (
             os.path.join("python", "mach"),
             os.path.join("third_party", "python", "packaging"),
-            os.path.join("third_party", "python", "pyparsing"),
         )
     ]
 
diff --git a/configure.py b/configure.py
index ee01e34f86f1..a3910dfe254b 100644
--- a/configure.py
+++ b/configure.py
@@ -18,7 +18,6 @@ sys.path.insert(0, os.path.join(base_dir, "python", "mach"))
 sys.path.insert(0, os.path.join(base_dir, "python", "mozboot"))
 sys.path.insert(0, os.path.join(base_dir, "python", "mozbuild"))
 sys.path.insert(0, os.path.join(base_dir, "third_party", "python", "packaging"))
-sys.path.insert(0, os.path.join(base_dir, "third_party", "python", "pyparsing"))
 sys.path.insert(0, os.path.join(base_dir, "third_party", "python", "six"))
 sys.path.insert(0, os.path.join(base_dir, "third_party", "python", "looseversion"))
 import mozpack.path as mozpath
diff --git a/python/mach/mach/test/test_site_activation.py b/python/mach/mach/test/test_site_activation.py
index e034a27b7666..3683338409eb 100644
--- a/python/mach/mach/test/test_site_activation.py
+++ b/python/mach/mach/test/test_site_activation.py
@@ -314,7 +314,6 @@ def _activation_context():
     required_mach_sys_paths = [
         topsrcdir / "python" / "mach",
         topsrcdir / "third_party" / "python" / "packaging",
-        topsrcdir / "third_party" / "python" / "pyparsing",
         topsrcdir / "third_party" / "python" / "pip",
     ]
 
diff --git a/python/mozperftest/mozperftest/runner.py b/python/mozperftest/mozperftest/runner.py
index 30789bfdca7f..b29f61257fef 100644
--- a/python/mozperftest/mozperftest/runner.py
+++ b/python/mozperftest/mozperftest/runner.py
@@ -49,14 +49,12 @@ def _activate_virtualenvs():
     """
 
     # We need the "mach" module to access the logic to parse virtualenv
-    # requirements. Since that depends on "packaging" (and, transitively,
-    # "pyparsing"), we add those to the path too.
+    # requirements. Since that depends on "packaging", we add that to the path too.
     sys.path[0:0] = [
         os.path.join(SRC_ROOT, module)
         for module in (
             os.path.join("python", "mach"),
             os.path.join("third_party", "python", "packaging"),
-            os.path.join("third_party", "python", "pyparsing"),
         )
     ]
 
diff --git a/python/sites/common.txt b/python/sites/common.txt
index 51c5e21af1ed..b1f8417521a5 100644
--- a/python/sites/common.txt
+++ b/python/sites/common.txt
@@ -40,7 +40,6 @@ vendored:third_party/python/ply
 vendored:third_party/python/pyasn1
 vendored:third_party/python/pyasn1_modules
 vendored:third_party/python/pylru
-vendored:third_party/python/pyparsing
 vendored:third_party/python/pyrsistent
 vendored:third_party/python/python_dateutil
 vendored:third_party/python/python_slugify
diff --git a/python/sites/docs.txt b/python/sites/docs.txt
index bc079f54275a..55ac66a8644b 100644
--- a/python/sites/docs.txt
+++ b/python/sites/docs.txt
@@ -65,7 +65,6 @@ vendored:third_party/python/mohawk
 vendored:third_party/python/mozilla_repo_urls
 vendored:third_party/python/packaging
 vendored:third_party/python/pkgutil_resolve_name
-vendored:third_party/python/pyparsing
 vendored:third_party/python/python_dateutil
 vendored:third_party/python/python_slugify
 vendored:third_party/python/redo
diff --git a/python/sites/lint.txt b/python/sites/lint.txt
index e9f0740ee7a1..8a710f47ad7e 100644
--- a/python/sites/lint.txt
+++ b/python/sites/lint.txt
@@ -17,7 +17,6 @@ vendored:third_party/python/mohawk
 vendored:third_party/python/mozilla_repo_urls
 vendored:third_party/python/multidict
 vendored:third_party/python/pathspec
-vendored:third_party/python/pyparsing
 vendored:third_party/python/pyrsistent
 vendored:third_party/python/python_dateutil
 vendored:third_party/python/python_slugify
diff --git a/python/sites/mach.txt b/python/sites/mach.txt
index 52904b5bef49..0b566364ae39 100644
--- a/python/sites/mach.txt
+++ b/python/sites/mach.txt
@@ -74,7 +74,6 @@ vendored:third_party/python/mozilla_version
 vendored:third_party/python/packaging
 vendored:third_party/python/pip
 vendored:third_party/python/pip_tools
-vendored:third_party/python/pyparsing
 vendored:third_party/python/python-hglib
 vendored:third_party/python/requests
 vendored:third_party/python/sentry_sdk
diff --git a/python/sites/python-test.txt b/python/sites/python-test.txt
index 3ab11a448176..b7068a1a5da7 100644
--- a/python/sites/python-test.txt
+++ b/python/sites/python-test.txt
@@ -41,7 +41,6 @@ vendored:third_party/python/ply
 vendored:third_party/python/pyasn1
 vendored:third_party/python/pyasn1_modules
 vendored:third_party/python/pylru
-vendored:third_party/python/pyparsing
 vendored:third_party/python/pyrsistent
 vendored:third_party/python/python_dateutil
 vendored:third_party/python/python_slugify